Test Directory

Anti-Glutamic Acid Decarboxylase Antibody

Containers - Adult

AAXXAANoImage.jpg
Sarstedt Monovette Serum Gel Tube (Brown Cap)
Volume Range

​4.9ml

Additive per Container

​Clotting activator/gel

Containers - Child

AAXXAANoImage.jpg
Sarstedt Monovette Serum Gel Tube (Brown Cap)
Volume Range

​4.9ml

Additive per Container

​Clotting activator/gel

Reference ranges

Anti-GAD

Normal <5 U/ml

Positive >5 U/ml

Please Note : 

 

GAD Antibodies:

 

Interpretive guidance for GAD autoantibodies tested in line with Diabetes pathway: (data from Pearson et al, Exeter lab data 2020)

 

Strong positive ≥ 64 U/ml

Weak positive ≥ 11 U/ml

Equivocal  5.1-10.9 U/ml

Laboratory Site

RIE
51 Little France Crescent
Old Dalkeith Road
Edinburgh
EH16 4SA
Telephone: 0131 536 1000

Special instructions for collection

Serum samples only please.

How to request

​Trak, ICE, Clinical Immunology request form.

Diabetic screen tests can only be requested via Hospital referrals.

Availability

​Normal working hours 9am-5pm Mon-Fri.

Anticipated turnaround

21 Days
 
 

What happens if the result is positive or abnormal

General additional information

​Diagnosis of Type 1 Diabetes Mellitus.

Tested alongside Anti-IA2 and Anti-ZnT8

Two forms of GAD, known as GAD65 and GAD67, are recognised. The current assay recognises antibodies to GAD65 which are found in T1DM and approximately 60% of patients with stiff-person syndrome.