Test Directory

Glomerular Basement Membrane Antibody

Containers - Adult

Sarstedt Monovette Serum Gel Tube (Brown Cap)	Volume Range 4.9mls Additive per Container Clotting activator/gel

Containers - Child

Sarstedt Monovette Serum Gel Tube (Brown Cap)	Volume Range 4.9ml Additive per Container Clotting activator/gel

Reference ranges

Anti-GBM

Normal Range <7 U/ml

Equivocal Range 7 - 10 U/ml

Positive Range >10 U/ml

Laboratory Site

RIE

51 Little France Crescent
Old Dalkeith Road
Edinburgh
EH16 4SA

Telephone: 0131 536 1000

How to request

Trak, ICE, Clinical Immunology request form.

Availability

Normal working hours 9am-5pm Mon-Fri.

Anticipated turnaround

Urgent same day/next day service available. Sample must be received in the lab by 1pm Mon and Fri. Prior notice must be given before a sample is sent.

Non urgent samples 7 Days.

What happens if the result is positive or abnormal

Reviewed and authorised by Consultant Immunologist.

Any urgent results are telephoned directly to the requesting clinician.

If 'new' positive the result is given to the Consultant Immunologist or Registrar

General additional information

Diagnosis of Goodpasture's Syndrome

Anti-GBM antibodies are found in the sera of the majority (>90%) of patients with Goodpasture's syndrome. The diagnosis must be confirmed by renal biopsy. They are also occasionally found in ANCA-associated disease, usually with MPO-ANCA but very rarely with PR3-ANCA.